Definition of «genomic rearrangements»

"Genomic rearrangements" refer to changes or rearrangements in the structure or arrangement of a person's DNA or genetic material. It involves alterations, such as deletions, duplications, inversions, or translocations, in specific segments of the DNA sequence, resulting in a modified genetic makeup. These changes can impact the functioning of genes and potentially lead to various genetic disorders or diseases.

Sentences with «genomic rearrangements»

The commercial tests were based on both Sanger sequencing and supplementary testing for large genomic rearrangements in both genes. (sciencedaily.com)
We excluded large genomic rearrangements from this analysis as those mutations span multiple bins and also undertook a subset analysis with and without missense mutations. (jamanetwork.com)
A new study published today describes how a complex genomic rearrangement causes a fascinating phenotype in chickens. (scilifelab.se)
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